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Area Biologicals & small molecules in drug research

 


Lipid Signalling
Prof. Dr. Dr.
Gerd Geißlinger

Prof. Dr.
Josef Pfeilschifter

Prof. Dr.
Dieter Steinhilber



Cardiovascular Signalling
Prof. Dr.
Ingrid Fleming

Prof. Dr.
Stefanie Dimmeler



Oncogenic Signalling
Prof. Dr.
Rolf Marschalek

Prof. Dr.
Hubert Serve

Prof. Dr.
Simone Fulda



Redox Signalling
Prof. Dr.
B. Brüne

Prof. Dr.
R. Brandes



Biologicals & small molecules in drug research
Prof. Dr. Dr.
Gerd Geisslinger

Prof. Dr.
Josef Pfeilschifter

Prof. Dr.
Heinfried Radeke

 


     GK 1172 Biologicals
 

Coordinators:

Prof. Dr. Dr. Gerd Geisslinger


Prof. Dr. Josef Pfeilschifter

Prof. Dr. Heinfried Radeke


In recent years, therapeutic biomolecules (biologicals or biopharmaceutical drugs) have had a great innovative potential and the number of newly approved biologicals has greatly extended. Most of these biologicals are protein drugs that act extracellularly, such as antibodies, cytokines and growth factors. Small molecules have long been the major focus of drug development, however there are still many diseases for which currently there is no cure available, and here small molecules are still in the main line of research.


Participating projects:

  • Research Training Group 1172 „Research, development and safety of biopharmaceutical drugs – Biologicals”

    Speaker: Prof. Dr. J. Pfeilschifter, funded by the DFG since 2005

    In the research training group especially innovative research on biologicals, such as the development of therapeutic RNAs, intracellularly active proteins and gene therapy, is brought together. Some research projects are carried out at the Georg-Speyer-Haus (GSH) in Frankfurt and the Paul-Ehrlich Institute in Langen.

  • Research Training Group TRIP: “Translational Research Innovation – Pharma“

    Speaker: Prof. Dr. Dr. G. Geisslinger, funded by the Else Kröner-Fresenius-Stiftung

    Major topics of this research training group are pain, multiple sclerosis, diabetes and autoimmune disorders.
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